Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii

Two new dimeric carbazole alkaloids, clausenawallines A and B, were isolated from the roots of Clausena wallichii. Their structures were elucidated by spectroscopic methods. Clausenawalline A was evaluated for its biological activities [anti-malaria (IC502.46 μg/mL), anti-TB (MIC 12.50 μg/mL)] and c...

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Main Authors:	Wisanu Maneerat, Thunwadee Ritthiwigrom, Sarot Cheenpracha, Uma Prawat, Surat Laphookhieo
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79957607206&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49706
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-49706
record_format	dspace
spelling	th-cmuir.6653943832-497062018-09-04T04:28:53Z Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii Wisanu Maneerat Thunwadee Ritthiwigrom Sarot Cheenpracha Uma Prawat Surat Laphookhieo Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Two new dimeric carbazole alkaloids, clausenawallines A and B, were isolated from the roots of Clausena wallichii. Their structures were elucidated by spectroscopic methods. Clausenawalline A was evaluated for its biological activities [anti-malaria (IC502.46 μg/mL), anti-TB (MIC 12.50 μg/mL)] and cytotoxicity against three human cancer cell lines [KB (IC507.87 μg/mL), MCF7 (IC5025.43 μg/mL), and NCI-H187 (IC5010.97 μg/mL)]. © 2011 Elsevier Ltd. All rights reserved. 2018-09-04T04:05:48Z 2018-09-04T04:05:48Z 2011-06-29 Journal 18733581 00404039 2-s2.0-79957607206 10.1016/j.tetlet.2011.04.064 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79957607206&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49706
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Wisanu Maneerat Thunwadee Ritthiwigrom Sarot Cheenpracha Uma Prawat Surat Laphookhieo Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
description	Two new dimeric carbazole alkaloids, clausenawallines A and B, were isolated from the roots of Clausena wallichii. Their structures were elucidated by spectroscopic methods. Clausenawalline A was evaluated for its biological activities [anti-malaria (IC502.46 μg/mL), anti-TB (MIC 12.50 μg/mL)] and cytotoxicity against three human cancer cell lines [KB (IC507.87 μg/mL), MCF7 (IC5025.43 μg/mL), and NCI-H187 (IC5010.97 μg/mL)]. © 2011 Elsevier Ltd. All rights reserved.
format	Journal
author	Wisanu Maneerat Thunwadee Ritthiwigrom Sarot Cheenpracha Uma Prawat Surat Laphookhieo
author_facet	Wisanu Maneerat Thunwadee Ritthiwigrom Sarot Cheenpracha Uma Prawat Surat Laphookhieo
author_sort	Wisanu Maneerat
title	Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
title_short	Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
title_full	Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
title_fullStr	Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
title_full_unstemmed	Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
title_sort	clausenawallines a and b, two new dimeric carbazole alkaloids from the roots of clausena wallichii
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79957607206&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49706
_version_	1681423458317107200

Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii

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