Clonal composition of neuroantigen-specific CD8+ and CD4+ T-cells in multiple sclerosis
Patients with multiple sclerosis (MS) show a high prevalence of myelin-reactive CD8+ and CD4+ T-cell responses, which are the putative effectors/modulators of CNS neuropathology. Utilizing a novel combination of short-term culture, CFSE-based sorting and anchored PCR, we evaluated clonal composition...
Saved in:
Main Authors: | Brian W. Biegler, Shirley X. Yan, Sterling B. Ortega, Deepani K. Tennakoon, Michael K. Racke, Nitin J. Karandikar |
---|---|
Format: | Journal |
Published: |
2018
|
Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79955666022&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50032 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Chiang Mai University |
Similar Items
-
Clonal composition of neuroantigen-specific CD8+ and CD4+ T-cells in multiple sclerosis
by: Biegler B., et al.
Published: (2017) -
Specificity of autoantibodies to epitopes of myelin proteins in multiple sclerosis
by: Permphan Dharmasaroja
Published: (2018) -
Clonal deletion prunes but does not eliminate self-specific ?? CD8+ T lymphocytes
by: Yu, W., et al.
Published: (2016) -
Current evidence of rituximab in the treatment of multiple sclerosis
by: Techa-angkoon P.
Published: (2023) -
Investigating axonal damage in multiple sclerosis by diffusion tensor spectroscopy
by: Emily T. Wood, et al.
Published: (2018)