Pairwise decomposition of residue interaction energies of single chain Fv with HIV-1 p17 epitope variants

Computational assisted modeling was carried out to investigate the importance of specific residues in the binding site of scFv. In this study, scFv against HIV-1 epitope at the C-terminal on p17 (scFv anti-p17) was used as a candidate molecule for evaluating the method. The wild-type p17 and its nin...

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Main Authors: Vannajan Sanghiran Lee, Panthip Tue-ngeun, Sawitree Nangola, Kuntida Kitidee, Jitrayut Jitonnom, Piyarat Nimmanpipug, Supat Jiranusornkul, Chatchai Tayapiwatana
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=74849100500&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50598
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Institution: Chiang Mai University