Influence of pr-M cleavage on the heterogeneity of extracellular dengue virus particles

• المؤلفون الرئيسيون: Jiraphan Junjhon, Thomas J. Edwards, Utaiwan Utaipat, Valorie D. Bowman, Heather A. Holdaway, Wei Zhang, Poonsook Keelapang, Chunya Puttikhunt, Rushika Perera, Paul R. Chipman, Watchara Kasinrerk, Prida Malasit, Richard J. Kuhn, Nopporn Sittisombut
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Immunology and Microbiology
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954972691&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50924
• المؤسسة: Chiang Mai University

During dengue virus replication, an incomplete cleavage of the envelope glycoprotein prM, generates a mixture of mature (prM-less) and prM-containing, immature extracellular particles. In this study, sequential immunoprecipitation and cryoelectron microscopy revealed a third type of extracellular pa...