Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities

A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data....

Full description

Saved in:
Bibliographic Details
Main Authors: Sanchai Nayyatip, Pak Thaichana, Mongkol Buayairaksa, Wirote Tuntiwechapikul, Puttinan Meepowpan, Narong Nuntasaen, Wilart Pompimon
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84860116503&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51410
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
id th-cmuir.6653943832-51410
record_format dspace
spelling th-cmuir.6653943832-514102018-09-04T06:03:52Z Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities Sanchai Nayyatip Pak Thaichana Mongkol Buayairaksa Wirote Tuntiwechapikul Puttinan Meepowpan Narong Nuntasaen Wilart Pompimon Biochemistry, Genetics and Molecular Biology Chemical Engineering Chemistry Computer Science A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors. 2018-09-04T06:01:30Z 2018-09-04T06:01:30Z 2012-04-01 Journal 14220067 2-s2.0-84860116503 10.3390/ijms13045010 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84860116503&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51410
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Chemical Engineering
Chemistry
Computer Science
spellingShingle Biochemistry, Genetics and Molecular Biology
Chemical Engineering
Chemistry
Computer Science
Sanchai Nayyatip
Pak Thaichana
Mongkol Buayairaksa
Wirote Tuntiwechapikul
Puttinan Meepowpan
Narong Nuntasaen
Wilart Pompimon
Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
description A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors.
format Journal
author Sanchai Nayyatip
Pak Thaichana
Mongkol Buayairaksa
Wirote Tuntiwechapikul
Puttinan Meepowpan
Narong Nuntasaen
Wilart Pompimon
author_facet Sanchai Nayyatip
Pak Thaichana
Mongkol Buayairaksa
Wirote Tuntiwechapikul
Puttinan Meepowpan
Narong Nuntasaen
Wilart Pompimon
author_sort Sanchai Nayyatip
title Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_short Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_full Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_fullStr Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_full_unstemmed Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_sort aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84860116503&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51410
_version_ 1681423764700528640