The antimicrobial peptide, LL-37, inhibits in vitro osteoclastogenesis

• Main Authors: C. Supanchart, S. Thawanaphong, A. Makeudom, J. G. Bolscher, K. Nazmi, U. Kornak, S. Krisanaprakornkit
• Format: Journal
• Published: 2018
• Subjects: Dentistry
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867728779&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51550
• Institution: Chiang Mai University

Uncoupled bone resorption leads to net alveolar bone loss in periodontitis. The deficiency of LL-37, the only human antimicrobial peptide in the cathelicidin family, in patients with aggressive periodontitis suggests that LL-37 may play a pivotal role in the inhibition of alveolar bone destruction i...