T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice

Objectives: Iron-overload cardiomyopathy is a major cause of morbidity and mortality in patients with thalassemia. However, the precise mechanisms of iron entry and sequestration in the heart are still unclear. Our previous study showed that Fe 2+ uptake in thalassemic cardiomyocytes are mainly medi...

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Main Authors: Sirinart Kumfu, Siriporn Chattipakorn, Kroekkiat Chinda, Suthat Fucharoen, Nipon Chattipakorn
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861187773&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51888
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Institution: Chiang Mai University