T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice

Objectives: Iron-overload cardiomyopathy is a major cause of morbidity and mortality in patients with thalassemia. However, the precise mechanisms of iron entry and sequestration in the heart are still unclear. Our previous study showed that Fe 2+ uptake in thalassemic cardiomyocytes are mainly me...

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Bibliographic Details
Main Authors: Sirinart Kumfu, Siriporn Chattipakorn, Kroekkiat Chinda, Suthat Fucharoen, Nipon Chattipakorn
Other Authors: Faculty of Medicine, Chiang Mai University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/14788
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Institution: Mahidol University