Semi-nested Taqman real-time quantitative PCR for noninvasive prenatal diagnosis of Bart's hydrops fetalis

• Main Authors: Sakorn Pornprasert, Kanyakan Sukunthamala, Naowarat Kunyanone, Sririchai Sittiprasert, Khanungnit Thungkham, Sumeth Junorse, Khachonsilp Pongsawatkul, Wisut Pattanaporn, Chantip Jitwong
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84856878134&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51969
• Institution: Chiang Mai University

Background: Non-invasive prenatal diagnosis based on detection of fetal cell-free DNA is limited when mother and father are both carriers for the same autosomal recessive mutation. Objective: Develop the semi-nested Taqman real-time PCR for quantification of α-thalassemia-1 SEA type deletion allele...