Inducible NOS mediates CNP-induced relaxation of intestinal myofibroblasts

• Main Authors: Yishi Chen, Taned Chitapanarux, Jianfeng Wu, Russell K. Soon, Andrew C. Melton, Hal F. Yee
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84878145650&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52235
• Institution: Chiang Mai University

Contraction of intestinal myofibroblasts (IMF) contributes to the development of strictures and fistulas seen in inflammatory bowel disease, but the mechanisms that regulate tension within these cells are poorly understood. In this study we investigated the role of nitric oxide (NO) signaling in C-t...