Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla

Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited an...

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Main Authors:	Sarot Cheenpracha, Thunwadee Ritthiwigrom, Surat Laphookhieo
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/52253
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-52253
record_format	dspace
spelling	th-cmuir.6653943832-522532018-09-04T09:35:48Z Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla Sarot Cheenpracha Thunwadee Ritthiwigrom Surat Laphookhieo Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy. 2018-09-04T09:22:43Z 2018-09-04T09:22:43Z 2013-04-26 Journal 15206025 01633864 2-s2.0-84876930059 10.1021/np3006937 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/52253
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Sarot Cheenpracha Thunwadee Ritthiwigrom Surat Laphookhieo Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
description	Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy.
format	Journal
author	Sarot Cheenpracha Thunwadee Ritthiwigrom Surat Laphookhieo
author_facet	Sarot Cheenpracha Thunwadee Ritthiwigrom Surat Laphookhieo
author_sort	Sarot Cheenpracha
title	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_short	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_full	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_fullStr	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_full_unstemmed	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_sort	alstoniaphyllines a-c, unusual nitrogenous derivatives from the bark of alstonia macrophylla
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/52253
_version_	1681423917345931264

Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla

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