Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla

• Main Authors: Sarot Cheenpracha, Thunwadee Ritthiwigrom, Surat Laphookhieo
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52253
• Institution: Chiang Mai University

Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited an...