Sensitive, simultaneous quantitation of two unlabeled DNA targets using a magnetic nanoparticle-enzyme sandwich assay

We report herein the development of a simple, sensitive colorimetric magnetic nanoparticle (MNP)-enzyme-based DNA sandwich assay that is suitable for simultaneous, label-free quantitation of two DNA targets down to 50 fM level. It can also effectively discriminate single-nucleotide polymorphisms (SN...

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Bibliographic Details
Main Authors: Yue Zhang, Chalermchai Pilapong, Yuan Guo, Zhenlian Ling, Oscar Cespedes, Philip Quirke, Dejian Zhou
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84884996190&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/52373
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Institution: Chiang Mai University