Reduced indinavir exposure during pregnancy

• Main Authors: Tim R. Cressey, Brookie M. Best, Jullapong Achalapong, Alice Stek, Jiajia Wang, Nantasak Chotivanich, Prapap Yuthavisuthi, Pornnapa Suriyachai, Sinart Prommas, David E. Shapiro, D. Heather Watts, Elizabeth Smith, Edmund Capparelli, Regis Kreitchmann, Mark Mirochnick
• Format: Journal
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84882644760&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52824
• Institution: Chiang Mai University

Aim: To describe the pharmacokinetics and safety of indinavir boosted with ritonavir (IDV/r) during the second and third trimesters of pregnancy and in the post-partum period. Methods: IMPAACT P1026s is an on-going, prospective, non-blinded study of antiretroviral pharmacokinetics (PK) in HIV-infect...