Pharmacokinetics of an increased atazanavir dose with and without tenofovir during the third trimester of pregnancy

• Main Authors: Regis Kreitchmann, Brookie M. Best, Jiajia Wang, Alice Stek, Edmund Caparelli, D. Heather Watts, Elizabeth Smith, David E. Shapiro, Steve Rossi, Sandra K. Burchett, Elizabeth Hawkins, Mark Byroads, Tim R. Cressey, Mark Mirochnick
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876294301&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52877
• Institution: Chiang Mai University

BACKGROUND: Reduced atazanavir exposure has been demonstrated during pregnancy with standard atazanavir/ritonavir dosing. We studied an increased dose during the third trimester of pregnancy. METHODS: International Maternal Pediatric Adolescent AIDS Clinical Trials Group 1026s is a prospective, nonb...