Cytotoxic aporphine alkaloids from leaves and twigs of pseuduvaria trimera (Craib)

• Main Authors: Wuttikrai Sesang, Sittiporn Punyanitya, Siripit Pitchuanchom, Phansuang Udomputtimekakul, Narong Nuntasaen, Ratana Banjerdpongchai, Benjawan Wudtiwai, Wilart Pompimon
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84904787784&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53283
• Institution: Chiang Mai University

From ethyl acetate-methanol extracts of leaves and twigs of Pseuduvaria trimera a new aporphine alkaloid; 8-hydroxy-1,4,5- Trimethoxy-7-oxoaporphine or 8-hydroxyartabonatine C (1) was isolated, together with the known 1,2,3- Trimethoxy-4,5- dioxo-6a,7-dehydroaporphine (ouregidione, 2). Their structu...