The associations of SEA-α thalassemia 1, XmnI-Gγ polymorphism and β-globin gene mutations with the clinical severity of β-thalassemia syndrome in Northern Thailand

• Main Authors: Thanusak Tatu, Waratip Sritong, Torpong Sa-Nguansermsri
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84902284949&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53777
• Institution: Chiang Mai University

At least three genetic factors including β-thalassemia mutations, α-thalassemia, and XmnI-Gγ polymorphism were shown to modify clinical symptoms in β-thalassemia disease. Objective: To determine associations of β-thalassemia mutations, SEA-α thalassemia 1, and XmnI-Gγ polymorphism, and clinical seve...