Inhibition of p38 MAPK activation protects cardiac mitochondria from ischemia/reperfusion injury

• Main Authors: Sarawut Kumphune, Sirirat Surinkaew, Siriporn C. Chattipakorn, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84943526975&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54113
• Institution: Chiang Mai University

© 2015 Informa Healthcare USA, Inc. Context: Cardiac cell death and fatal arrhythmias during myocardial ischemia/reperfusion (I/R) can be reduced by p38 MAPK inhibition. However, the effects of p38 MAPK inhibition on cardiac mitochondria have not been investigated. Objective: We tested the hypothesi...