Generation and preclinical immunogenicity study of dengue type 2 virus-like particles derived from stably transfected mosquito cells

• Main Authors: Amporn Suphatrakul, Thippawan Yasanga, Poonsook Keelapang, Rungtawan Sriburi, Thaneeya Roytrakul, Rojjanaporn Pulmanausahakul, Utaiwan Utaipat, Yanee Kawilapan, Chunya Puttikhunt, Watchara Kasinrerk, Sutee Yoksan, Prasert Auewarakul, Prida Malasit, Nicha Charoensri, Nopporn Sittisombut
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Veterinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84943452553&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/54114
• Institution: Chiang Mai University

© 2015 Elsevier Ltd. Recent phase IIb/III trials of a tetravalent live attenuated vaccine candidate revealed a need for improvement in the stimulation of protective immunity against diseases caused by dengue type 2 virus (DENV-2). Our attempts to develop particulate antigens for possibly supplementi...