Antifungal of modified neolignans from Mitrephora wangii Hu

© 2016, The Korean Society for Applied Biological Chemistry. Chromatographic separation of leaves and twigs from M. wangii had led to the isolation of conocarpan (1) and 3′-methoxyconocarpan (2). These structures were assigned on the basis of spectroscopic methods. Compound 1 was modified by organic...

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Bibliographic Details
Main Authors: Saksri Sanyacharernkul, Sirinapa Nantapap, Kallaya Sangrueng, Narong Nuntasaen, Wilart Pompimon, Puttinan Meepowpan
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84977566665&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/55200
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Institution: Chiang Mai University
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Summary:© 2016, The Korean Society for Applied Biological Chemistry. Chromatographic separation of leaves and twigs from M. wangii had led to the isolation of conocarpan (1) and 3′-methoxyconocarpan (2). These structures were assigned on the basis of spectroscopic methods. Compound 1 was modified by organic reactions and the modified compound 5 exhibited potent antifungal, Pyricularia oryzae. The method used poisoned food technique with mycelial growth inhibition for 14 days, 57 % (100 ppm). Compound 5 was stronger than mancozeb which the fungi toxicity drug used as a positive control.