A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload

A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload

© 2016 IBRO Iron-overload can cause cognitive impairment due to blood–brain barrier (BBB) breakdown and brain mitochondrial dysfunction. Although deferiprone (DFP) has been shown to exert neuroprotection, the head-to-head comparison among iron chelators used clinically on brain iron-overload has not...

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Bibliographic Details
Main Authors: Jirapas Sripetchwandee, Suwakon Wongjaikam, Warunsorn Krintratun, Nipon Chattipakorn, Siriporn C. Chattipakorn
Format: Journal
Published: 2018
Subjects:
Neuroscience
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978715654&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56256
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978715654&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56256

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