Vagus Nerve Stimulation Improves Cardiac Function by Preventing Mitochondrial Dysfunction in Obese-Insulin Resistant Rats

• Main Authors: Bencharunan Samniang, Krekwit Shinlapawittayatorn, Titikorn Chunchai, Wanpitak Pongkan, Sirinart Kumfu, Siriporn C. Chattipakorn, Bruce H. Kenknight, Nipon Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84956654538&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56373
• Institution: Chiang Mai University

Long-term high-fat diet (HFD) consumption leads to not only obese-insulin resistance, but also impaired left ventricular (LV) function. Vagus nerve stimulation (VNS) has been shown to exert cardioprotection. However, its effects on the heart and metabolic parameters under obese-insulin resistant con...