The impact of genetic polymorphisms on CYP1A2 activity in humans: a systematic review and meta-analysis

• المؤلفون الرئيسيون: Nut Koonrungsesomboon, Rapheephorn Khatsri, Penwisa Wongchompoo, Supanimit Teekachunhatean
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85039172574&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56653

© 2017 Macmillan Publishers Limited, part of Springer Nature A large interindividual variation in the activity of cytochrome P450 1A2 (CYP1A2) raises concern about therapeutic failure or toxicity when medical professionals prescribe drugs extensively metabolized by CYP1A2. To date, a number of studi...