Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities

Nephelium lappaceum is a tropical fruit whose peel possesses antioxidant properties. Experiments on the isolation and identification of the active constituents were conducted, and on their antioxidant activity using a lipid peroxidation inhibition assay. The methanolic extract of N. lappaceum peels...

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Main Authors: Thitilertdecha N., Teerawutgulrag A., Kilburn J.D., Rakariyatham N.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-77950363308&partnerID=40&md5=a2811c0ee6c026fbdc4c460228edb997
http://www.ncbi.nlm.nih.gov/pubmed/20335993
http://cmuir.cmu.ac.th/handle/6653943832/5666
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-56662014-08-30T03:23:17Z Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities Thitilertdecha N. Teerawutgulrag A. Kilburn J.D. Rakariyatham N. Nephelium lappaceum is a tropical fruit whose peel possesses antioxidant properties. Experiments on the isolation and identification of the active constituents were conducted, and on their antioxidant activity using a lipid peroxidation inhibition assay. The methanolic extract of N. lappaceum peels exhibited strong antioxidant properties. Sephadex LH-20 chromatography was utilized in the isolation of each constituent and the antioxidant properties of each was studied. The isolated compounds were identified as ellagic acid (EA) (1), corilagin (2) and geraniin (3). These compounds accounted for 69.3% of methanolic extract, with geraniin (56.8%) as the major component, and exhibited much greater antioxidant activities than BHT in both lipid peroxidation (77-186 fold) and DPPH• (42-87 fold) assays. The results suggest that the isolated ellagitannins, as the principal components of rambutan peels, could be further utilized as both a medicine and in the food industry. © 2010 by the authors. 2014-08-30T03:23:17Z 2014-08-30T03:23:17Z 2010 Article 14203049 10.3390/molecules15031453 20335993 MOLEF http://www.scopus.com/inward/record.url?eid=2-s2.0-77950363308&partnerID=40&md5=a2811c0ee6c026fbdc4c460228edb997 http://www.ncbi.nlm.nih.gov/pubmed/20335993 http://cmuir.cmu.ac.th/handle/6653943832/5666 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Nephelium lappaceum is a tropical fruit whose peel possesses antioxidant properties. Experiments on the isolation and identification of the active constituents were conducted, and on their antioxidant activity using a lipid peroxidation inhibition assay. The methanolic extract of N. lappaceum peels exhibited strong antioxidant properties. Sephadex LH-20 chromatography was utilized in the isolation of each constituent and the antioxidant properties of each was studied. The isolated compounds were identified as ellagic acid (EA) (1), corilagin (2) and geraniin (3). These compounds accounted for 69.3% of methanolic extract, with geraniin (56.8%) as the major component, and exhibited much greater antioxidant activities than BHT in both lipid peroxidation (77-186 fold) and DPPH• (42-87 fold) assays. The results suggest that the isolated ellagitannins, as the principal components of rambutan peels, could be further utilized as both a medicine and in the food industry. © 2010 by the authors.
format Article
author Thitilertdecha N.
Teerawutgulrag A.
Kilburn J.D.
Rakariyatham N.
spellingShingle Thitilertdecha N.
Teerawutgulrag A.
Kilburn J.D.
Rakariyatham N.
Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities
author_facet Thitilertdecha N.
Teerawutgulrag A.
Kilburn J.D.
Rakariyatham N.
author_sort Thitilertdecha N.
title Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities
title_short Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities
title_full Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities
title_fullStr Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities
title_full_unstemmed Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities
title_sort identification of major phenolic compounds from nephelium lappaceum l. and their antioxidant activities
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-77950363308&partnerID=40&md5=a2811c0ee6c026fbdc4c460228edb997
http://www.ncbi.nlm.nih.gov/pubmed/20335993
http://cmuir.cmu.ac.th/handle/6653943832/5666
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