Diet, gut microbiota and cognition

© 2016, Springer Science+Business Media New York. The consumption of a diet high in fat and sugar can lead to the development of obesity, type 2 diabetes mellitus (T2DM), cardiovascular disease and cognitive decline. In the human gut, the trillions of harmless microorganisms harboured in the host’s...

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Main Authors: Cicely Proctor, Parameth Thiennimitr, Nipon Chattipakorn, Siriporn C. Chattipakorn
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/56800
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-568002018-09-05T03:51:04Z Diet, gut microbiota and cognition Cicely Proctor Parameth Thiennimitr Nipon Chattipakorn Siriporn C. Chattipakorn Biochemistry, Genetics and Molecular Biology Medicine Neuroscience © 2016, Springer Science+Business Media New York. The consumption of a diet high in fat and sugar can lead to the development of obesity, type 2 diabetes mellitus (T2DM), cardiovascular disease and cognitive decline. In the human gut, the trillions of harmless microorganisms harboured in the host’s gastrointestinal tract are called the ‘gut microbiota’. Consumption of a diet high in fat and sugar changes the healthy microbiota composition which leads to an imbalanced microbial population in the gut, a phenomenon known as “gut dysbiosis”. It has been shown that certain types of gut microbiota are linked to the pathogenesis of obesity. In addition, long-term consumption of a high fat diet is associated with cognitive decline. It has recently been proposed that the gut microbiota is part of a mechanistic link between the consumption of a high fat diet and the impaired cognition of an individual, termed “microbiota-gut-brain axis”. In this complex relationship between the gut, the brain and the gut microbiota, there are several types of gut microbiota and host mechanisms involved. Most of these mechanisms are still poorly understood. Therefore, this review comprehensively summarizes the current evidence from mainly in vivo (rodent and human) studies of the relationship between diet, gut microbiota and cognition. The possible mechanisms that the diet and the gut microbiota have on cognition are also presented and discussed. 2018-09-05T03:30:25Z 2018-09-05T03:30:25Z 2017-02-01 Journal 15737365 08857490 2-s2.0-84990841839 10.1007/s11011-016-9917-8 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84990841839&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/56800
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience
Cicely Proctor
Parameth Thiennimitr
Nipon Chattipakorn
Siriporn C. Chattipakorn
Diet, gut microbiota and cognition
description © 2016, Springer Science+Business Media New York. The consumption of a diet high in fat and sugar can lead to the development of obesity, type 2 diabetes mellitus (T2DM), cardiovascular disease and cognitive decline. In the human gut, the trillions of harmless microorganisms harboured in the host’s gastrointestinal tract are called the ‘gut microbiota’. Consumption of a diet high in fat and sugar changes the healthy microbiota composition which leads to an imbalanced microbial population in the gut, a phenomenon known as “gut dysbiosis”. It has been shown that certain types of gut microbiota are linked to the pathogenesis of obesity. In addition, long-term consumption of a high fat diet is associated with cognitive decline. It has recently been proposed that the gut microbiota is part of a mechanistic link between the consumption of a high fat diet and the impaired cognition of an individual, termed “microbiota-gut-brain axis”. In this complex relationship between the gut, the brain and the gut microbiota, there are several types of gut microbiota and host mechanisms involved. Most of these mechanisms are still poorly understood. Therefore, this review comprehensively summarizes the current evidence from mainly in vivo (rodent and human) studies of the relationship between diet, gut microbiota and cognition. The possible mechanisms that the diet and the gut microbiota have on cognition are also presented and discussed.
format Journal
author Cicely Proctor
Parameth Thiennimitr
Nipon Chattipakorn
Siriporn C. Chattipakorn
author_facet Cicely Proctor
Parameth Thiennimitr
Nipon Chattipakorn
Siriporn C. Chattipakorn
author_sort Cicely Proctor
title Diet, gut microbiota and cognition
title_short Diet, gut microbiota and cognition
title_full Diet, gut microbiota and cognition
title_fullStr Diet, gut microbiota and cognition
title_full_unstemmed Diet, gut microbiota and cognition
title_sort diet, gut microbiota and cognition
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84990841839&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/56800
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