Selective formation of homo- and heterobivalent peptidomimetics

• Main Authors: Pattarawarapan M., Reyes S., Xia Z., Zaccaro M.C., Saragovi H.U., Burgess K.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-0042732952&partnerID=40&md5=a7518ad80b4161582f28e5caf4ff337a; http://cmuir.cmu.ac.th/handle/6653943832/5978
• Institution: Chiang Mai University

Methodology is presented for assembling fluorescently labeled bivalent molecules from monovalent constituents, without side chain protection or coupling agents. To illustrate the procedure, a series of bivalent peptidomimetics directed toward the Trk receptors were prepared and screened via fluoresc...