Detection of β-thalassemia mutations using a multiplex amplification refractory mutation system assay

• المؤلفون الرئيسيون: Saisiri Mirasena, Dawan Shimbhu, Mondhon Sanguansermsri, Torpong Sanguansermsri
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Medicine
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=47949088545&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60162

We developed two sets of a multiplex amplification refractory mutation system (M-ARMS) assay to identify specific β-thalassemia (β-thal) mutations that are common in Thailand. The first one was for the detection of mutants with codon 17 (A>T), IV S-I-1 (G >T)), codons 41/42 (-TCT T) and codons...