Interobserver reproducibility in determining p16 overexpression in cervical lesions: Use of a combined scoring method

• Main Authors: Songkhun Vinyuvat, Anant Karalak, Cheepsumon Suthipintawong, Kobkul Tungsinmunkong, Pilaiwan Kleebkaow, Prasert Trivijitsilp, Sumalee Siriaunkgul, Surang Triratanachat, Surapan Khunamornpong, Tuenjai Chuangsuwanich, Jongkolnee Settakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=66149089609&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60212
• Institution: Chiang Mai University

Objectives: To evaluate interobserver reproducibility of a combined scoring method for immunohistochemical interpretation of p16 overexpression in cervical lesions. Materials and methods: p16 immunostaining was performed in cervical samples from 183 patients, including 69 normal, 42 low grade squamo...