Interobserver reproducibility in determining p16 overexpression in cervical lesions: Use of a combined scoring method

• Main Authors: Songkhun Vinyuvat, Anant Karalak, Cheepsumon Suthipintawong, Kobkul Tungsinmunkong, Pilaiwan Kleebkaow, Prasert Trivijitsilp, Sumalee Siriaunkgul, Surang Triratanachat, Surapan Khunamornpong, Tuenjai Chuangsuwanich, Jongkolnee Settakorn
• Other Authors: Thailand Ministry of Public Health
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/19015
• Institution: Mahidol University

Objectives: To evaluate interobserver reproducibility of a combined scoring method for immunohistochemical interpretation of p16 overexpression in cervical lesions. Materials and methods: p16 immunostaining was performed in cervical samples from 183 patients, including 69 normal, 42 low grade squamo...