Novel anti-dengue monoclonal antibody recognizing conformational structure of the prM-E heterodimeric complex of dengue virus

• Main Authors: Chunya Puttikhunt, Poonsook Keelapang, Nuanpan Khemnu, Nopporn Sittisombut, Watchara Kasinrerk, Prida Malasit
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=36849036001&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60488
• Institution: Chiang Mai University

An interaction between the premembrane (prM) and envelope (E) glycoproteins as prM-E heterodimer is required for proper folding and transport of E during the formation and release of new flaviviral progeny. More evidence, however, is needed to confirm this interaction of prM and E during dengue viru...