Mass spectrometry-based detection of hemoglobin E mutation by allele-specific base extension reaction
Background: The specific detection of a minor population of mutant DNA molecules requires methods of high specificity and sensitivity. While the single-allele base extension reaction (SABER) was shown to be useful for the detection of certain beta-thalassemia mutations, we encountered problems with...
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Main Authors: | , , , , , , , |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=36649013864&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/60870 |
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Institution: | Chiang Mai University |