Two related but distinct chondroitin sulfate mimetope octasaccharide sequences recognized by monoclonal antibody WF6

• المؤلفون الرئيسيون: Peraphan Pothacharoen, Kittiwan Kalayanamitra, Sarama S. Deepa, Shigeyuki Fukui, Tomohide Hattori, Nobuhiro Fukushima, Timothy Hardingham, Prachya Kongtawelert, Kazuyuki Sugahara
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=36849023787&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60872

Chondroitin sulfate (CS) proteoglycans are major components of cartilage and other connective tissues. The monoclonal antibody WF6, developed against embryonic shark cartilage CS, recognizes an epitope in CS chains, which is expressed in ovarian cancer and variably in joint diseases. To elucidate th...