A novel one-step biotransformation of cortexolone-21-acetate to hydrocortisone acetate using Cunninghamella blakesleeana ATCC 8688a

• Main Authors: Jiradej Manosroi, Suda Saowakhon, Aranya Manosroi
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34248589992&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60891
• Institution: Chiang Mai University

A novel one-step biotransformation of cortexolone-21-acetate to hydrocortisone acetate by nine microorganisms in various culturing conditions including the inoculum density, pH of the medium, amounts of the precursor and surfactant or oil containing medium was presented. The microorganisms used were...