Acute and subchronic toxicity study of the water extract from dried fruits of Piper nigrum L. in rats

• Main Authors: Siharat Chunlaratthanaphorn, Nirush Lertprasertsuke, Umarat Srisawat, Amornnat Thuppia, Anongnad Ngamjariyawat, Nadthaganya Suwanlikhid, Kanjana Jaijoy
• Format: Journal
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34248382578&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61411
• Institution: Chiang Mai University

The study was carried out to evaluate acute and subchronic toxicities of the water extract from the dried fruits of Piper nigrum L. A single oral administration of the extract at a dose of 5,000 mg/kg body weight (5 male, 5 female) did not produce signs of toxicity, behavioral changes, mortality, ch...