Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids
Multidrug resistance (MDR) is a phenomenon that is often associated with decreased intracellular drug accumulation in patient's tumor cells resulting from enhanced drug efflux. It is related to the overexpression of a membrane protein, Pglycoprotein (Pgp-170), on the surface of tumor cells, the...
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2018
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