Cost-effective flow injection spectrophotometric assay of iron content in pharmaceutical preparations using salicylate reagent

• Main Authors: Udnan Y., Jakmunee J., Jayasavati S., Christian G.D., Synovec R.E., Grudpan K.
• Format: Conference or Workshop Item
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-7044225834&partnerID=40&md5=34c48f9227186a46f5c036de102ac237; http://www.ncbi.nlm.nih.gov/pubmed/18969735; http://cmuir.cmu.ac.th/handle/6653943832/6246
• Institution: Chiang Mai University

A new flow injection procedure for an assay of Fe(III) by using salicylate obtained from antipyretic powder, which is a cheap and easily available reagent, is proposed. A red complex was continuously monitored by a laboratory-made green LED colorimeter. A linear calibration was obtained in the range of 1-20 mg Fe l-1 with a detection limit of 0.5 mg Fe l-1 and R.S.D.s of 1.4-5.4% (n=3, for 1-20 mg Fe l-1). The new procedure was applied to assay iron contents in pharmaceutical preparations. The results were in good agreement with those of the USP standard method. © 2004 Published by Elsevier B.V.