Mechanochemical synthesis of primary amides from carboxylic acids using TCT/NH<inf>4</inf>SCN

• Main Authors: Subin Jaita, Wong Phakhodee, Neeranuch Chairungsi, Mookda Pattarawarapan
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052623821&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62562
• Institution: Chiang Mai University

© 2018 A facile and effective approach toward the synthesis of primary amides from carboxylic acids has been developed. In the presence of 2,4,6-trichloro-1,3,5-triazine, a combination of ammonium thiocyanate and potassium carbonate led to the rapid conversion of carboxylic acids into the correspond...