Green tea extract modulates oxidative tissue injury in beta-thalassemic mice by chelation of redox iron and inhibition of lipid peroxidation

• Main Authors: Pimpisid Koonyosying, Sarawut Kongkarnka, Chairat Uthaipibull, Saovaros Svasti, Suthat Fucharoen, Somdet Srichairatanakool
• Format: Journal
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85054613793&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62866
• Institution: Chiang Mai University

© 2018 Elsevier Masson SAS Iron overload in patients with β-thalassemia can cause oxidative organ dysfunction. Iron chelation along with antioxidant supplementation can ameliorate such complications and prolong lives. Green tea extract (GTE) rich in epigallocatechin-3-gallate (EGCG) exhibits anti-ox...