A convenient one-pot synthesis of: N -substituted amidoximes and their application toward 1,2,4-oxadiazol-5-ones

• Main Authors: Wong Phakhodee, Chuthamat Duangkamol, Nitaya Wiriya, Mookda Pattarawarapan
• Format: Journal
• Published: 2018
• Subjects: Chemical Engineering; Chemistry
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057227709&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62963
• Institution: Chiang Mai University

© 2018 The Royal Society of Chemistry. The first direct one-pot approach for the synthesis of N-substituted amidoximes from secondary amides or the intermediate amides has been developed. Through the Ph3P-I2-mediated dehydrative condensation, a variety of N-aryl and N-alkyl amidoximes (R1(CNOH)NHR2,...