Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis

© 2019 American Chemical Society and American Society of Pharmacognosy. The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A-K (1-11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known co...

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Main Authors:	Chiramet Auranwiwat, Puttandon Wongsomboon, Thanaphat Thaima, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Anthony C. Willis, Surat Laphookhieo, Stephen G. Pyne, Thunwadee Limtharakul
Format:	Journal
Published:	2019
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060556746&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/63579
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-63579
record_format	dspace
spelling	th-cmuir.6653943832-635792019-03-18T02:25:31Z Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis Chiramet Auranwiwat Puttandon Wongsomboon Thanaphat Thaima Roonglawan Rattanajak Sumalee Kamchonwongpaisan Anthony C. Willis Surat Laphookhieo Stephen G. Pyne Thunwadee Limtharakul Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics © 2019 American Chemical Society and American Society of Pharmacognosy. The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A-K (1-11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known compounds (13-21) were also isolated. Three of the isolated compounds are chlorinated polyoxygenated cyclohexenes. The structures of these compounds were determined using spectroscopic methods and, in some cases (compounds 2, 6, 8, and 10), single-crystal X-ray crystallographic structural analysis or chemical correlation (compounds 6 and 7). Compounds 6 and 7 were both isolated as scalemic mixtures (ee 23-24%). 2019-03-18T02:21:10Z 2019-03-18T02:21:10Z 2019-01-25 Journal 15206025 01633864 2-s2.0-85060556746 10.1021/acs.jnatprod.8b00794 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060556746&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/63579
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Chiramet Auranwiwat Puttandon Wongsomboon Thanaphat Thaima Roonglawan Rattanajak Sumalee Kamchonwongpaisan Anthony C. Willis Surat Laphookhieo Stephen G. Pyne Thunwadee Limtharakul Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
description	© 2019 American Chemical Society and American Society of Pharmacognosy. The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A-K (1-11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known compounds (13-21) were also isolated. Three of the isolated compounds are chlorinated polyoxygenated cyclohexenes. The structures of these compounds were determined using spectroscopic methods and, in some cases (compounds 2, 6, 8, and 10), single-crystal X-ray crystallographic structural analysis or chemical correlation (compounds 6 and 7). Compounds 6 and 7 were both isolated as scalemic mixtures (ee 23-24%).
format	Journal
author	Chiramet Auranwiwat Puttandon Wongsomboon Thanaphat Thaima Roonglawan Rattanajak Sumalee Kamchonwongpaisan Anthony C. Willis Surat Laphookhieo Stephen G. Pyne Thunwadee Limtharakul
author_facet	Chiramet Auranwiwat Puttandon Wongsomboon Thanaphat Thaima Roonglawan Rattanajak Sumalee Kamchonwongpaisan Anthony C. Willis Surat Laphookhieo Stephen G. Pyne Thunwadee Limtharakul
author_sort	Chiramet Auranwiwat
title	Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
title_short	Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
title_full	Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
title_fullStr	Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
title_full_unstemmed	Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
title_sort	polyoxygenated cyclohexenes and their chlorinated derivatives from the leaves of uvaria cherrevensis
publishDate	2019
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060556746&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/63579
_version_	1681425921539571712

Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis

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