QM/MM molecular modelling on mutation effect of chorismate synthase enzyme catalysis

© 2018 Elsevier Inc. Chorismate synthase (CS) catalyzes the conversion of 5-enolpyruvylshikimate-3-phosphate (EPSP) to chorismate which is a key intermediate in the biosynthesis of aromatic amino acids. CS enzyme is a new target for antibacterial drugs. Even though several reaction mechanisms have b...

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Bibliographic Details
Main Authors: Narin Lawan, Pongsakorn Chasing, Jirapat Santatiwongchai, Sairoong Muangpil
Format: Journal
Published: 2019
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059026813&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/63611
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Institution: Chiang Mai University