Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation

The aim of this study was to examine for the first time antioxidant properties from ethanol extracts of Achillea grandifolia flowers, leaves and stems using various antioxidant capacity methods. Subsequently, phenolic compounds in the extracts were identified for the first time by ESI-Q-TOF LC/MS an...

Full description

Saved in:
Bibliographic Details
Main Authors: Duygu Taşkın, Dilek B. Alkaya, Emre Dölen
Format: บทความวารสาร
Language:English
Published: Science Faculty of Chiang Mai University 2019
Online Access:http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8749
http://cmuir.cmu.ac.th/jspui/handle/6653943832/64022
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
Language: English
id th-cmuir.6653943832-64022
record_format dspace
spelling th-cmuir.6653943832-640222019-05-07T09:59:43Z Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation Duygu Taşkın Dilek B. Alkaya Emre Dölen The aim of this study was to examine for the first time antioxidant properties from ethanol extracts of Achillea grandifolia flowers, leaves and stems using various antioxidant capacity methods. Subsequently, phenolic compounds in the extracts were identified for the first time by ESI-Q-TOF LC/MS and HPLC-DAD methods. The phenolic compounds in A. grandifolia was identified as quercetagetin 3,6-dimethyl ether, quercetin, luteolin-7-O glucoside, rutin, luteolin, caffeic acid, chlorogenic acid, salicylic acid and dicaffeoylquinic acids. Additionally, HPLC-DAD quantification of major phenolic acids and flavonoids was carried out to all of extracts. Compherensive HPLC-DAD-MS analysis showed that flower extract represent the most abundant phenolic compounds. Also, our study clearly demonstrated that the flower showed better antioxidant effects, total phenolic and flavonoid contents than leaf and stem. Therefore, the flower extract could be a rich source of natural antioxidants and is worthy of further studies that may lead to the discovery of new natural antioxidants. 2019-05-07T09:59:43Z 2019-05-07T09:59:43Z 2018 บทความวารสาร 0125-2526 http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8749 http://cmuir.cmu.ac.th/jspui/handle/6653943832/64022 Eng Science Faculty of Chiang Mai University
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The aim of this study was to examine for the first time antioxidant properties from ethanol extracts of Achillea grandifolia flowers, leaves and stems using various antioxidant capacity methods. Subsequently, phenolic compounds in the extracts were identified for the first time by ESI-Q-TOF LC/MS and HPLC-DAD methods. The phenolic compounds in A. grandifolia was identified as quercetagetin 3,6-dimethyl ether, quercetin, luteolin-7-O glucoside, rutin, luteolin, caffeic acid, chlorogenic acid, salicylic acid and dicaffeoylquinic acids. Additionally, HPLC-DAD quantification of major phenolic acids and flavonoids was carried out to all of extracts. Compherensive HPLC-DAD-MS analysis showed that flower extract represent the most abundant phenolic compounds. Also, our study clearly demonstrated that the flower showed better antioxidant effects, total phenolic and flavonoid contents than leaf and stem. Therefore, the flower extract could be a rich source of natural antioxidants and is worthy of further studies that may lead to the discovery of new natural antioxidants.
format บทความวารสาร
author Duygu Taşkın
Dilek B. Alkaya
Emre Dölen
spellingShingle Duygu Taşkın
Dilek B. Alkaya
Emre Dölen
Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
author_facet Duygu Taşkın
Dilek B. Alkaya
Emre Dölen
author_sort Duygu Taşkın
title Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
title_short Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
title_full Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
title_fullStr Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
title_full_unstemmed Evaluation of Antioxidant Capacity and Analysis of Major Phenolic Compounds in Achillea grandifolia by HPLC-DAD with Q-TOF LC/MS Confirmation
title_sort evaluation of antioxidant capacity and analysis of major phenolic compounds in achillea grandifolia by hplc-dad with q-tof lc/ms confirmation
publisher Science Faculty of Chiang Mai University
publishDate 2019
url http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8749
http://cmuir.cmu.ac.th/jspui/handle/6653943832/64022
_version_ 1681426004031045632