Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid
In this contribution, salicylic acid (SA) has been used to catalyze synthesis of a series of biologically relevant 3,3¢-bis(indolyl)methanes (BIMs) via the electrophilic substitution of indole derivatives on aldehyde compounds. The optimum catalyst loading was observed at 15 mol%. The procedure is s...
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Science Faculty of Chiang Mai University
2019
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| Online Access: | http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8759 http://cmuir.cmu.ac.th/jspui/handle/6653943832/64035 |
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th-cmuir.6653943832-640352019-05-07T09:59:44Z Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid Hoda Banari Hamzeh Kiyani Alireza Pourali In this contribution, salicylic acid (SA) has been used to catalyze synthesis of a series of biologically relevant 3,3¢-bis(indolyl)methanes (BIMs) via the electrophilic substitution of indole derivatives on aldehyde compounds. The optimum catalyst loading was observed at 15 mol%. The procedure is simple and the expected bis-heterocyclic compounds were isolated in good to high yields. The present protocol provides the advantages of convenience, mild reaction conditions, eco-friendliness, energy-saving, and no use of hazardous solvents. 2019-05-07T09:59:44Z 2019-05-07T09:59:44Z 2018 บทความวารสาร 0125-2526 http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8759 http://cmuir.cmu.ac.th/jspui/handle/6653943832/64035 Eng Science Faculty of Chiang Mai University |
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Chiang Mai University |
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Chiang Mai University Library |
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Thailand |
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English |
| description |
In this contribution, salicylic acid (SA) has been used to catalyze synthesis of a series of biologically relevant 3,3¢-bis(indolyl)methanes (BIMs) via the electrophilic substitution of indole derivatives on aldehyde compounds. The optimum catalyst loading was observed at 15 mol%. The procedure is simple and the expected bis-heterocyclic compounds were isolated in good to high yields. The present protocol provides the advantages of convenience, mild reaction conditions, eco-friendliness, energy-saving, and no use of hazardous solvents. |
| format |
บทความวารสาร |
| author |
Hoda Banari Hamzeh Kiyani Alireza Pourali |
| spellingShingle |
Hoda Banari Hamzeh Kiyani Alireza Pourali Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
| author_facet |
Hoda Banari Hamzeh Kiyani Alireza Pourali |
| author_sort |
Hoda Banari |
| title |
Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
| title_short |
Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
| title_full |
Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
| title_fullStr |
Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
| title_full_unstemmed |
Green Synthesis of Bis(indolyl)methanes Catalysed by Salicylic Acid |
| title_sort |
green synthesis of bis(indolyl)methanes catalysed by salicylic acid |
| publisher |
Science Faculty of Chiang Mai University |
| publishDate |
2019 |
| url |
http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8759 http://cmuir.cmu.ac.th/jspui/handle/6653943832/64035 |
| _version_ |
1681426006481567744 |