Rapid and Efficient Synthesis of 4-[(tri fluorine methyl)-2, 6-diNitro Phenyl Amino]-4, 3-di hydro-6-methyl-3-thioxo-1, 2, 4-Triazine-5-ones Derivatives by Nano MgO under Microwave Irradiation

• Main Authors: Shima Ajami, Milad Taheri, Mehdi Hadjihoseyni
• Format: บทความวารสาร
• Language: English
• Published: Science Faculty of Chiang Mai University 2019
• Online Access: http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=9330; http://cmuir.cmu.ac.th/jspui/handle/6653943832/64172
• Institution: Chiang Mai University

In this research work, 4-[(tri fluorine methyl)-2,6-di nitro phenyl amino]-4,3-di hydro-6-methyl-3-thioxo-1,2,4-Triazine-5-one was produced from the reaction between 2-chloro-1,3-di nitro-5-triflouro methyl benzene and 4-amino-6-methyl-5-one-3-thion-1,2,4-Triazine through two methods (1-reflux & 2-microwave) in the presence of suitable solvents Using Nano catalyst MgO under microwave conditions have been reported. The MAOS method is more effective in synthesizing these compounds than the conventional method regarding to the higher chemical yields of products (54% to 96%) and the shorter reaction times (7 to 10 minutes). Structural, optical and nanostructures by X-ray diffraction X (XRD), scanning electron microscopy (SEM). The 1H-NMR and other methods like FT-IR and Mass spectroscopy have determined all of the compounds. Obtained results of synthesized compounds showed that reactions were carried out with suitable speed and range of products, low response time, high catalytic activity, and excellent products and environmentally friendly the results of this protocol are very important.