Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles

An enantioselective Michael addition reaction of diphenylphosphine to substituted alkenylisoxazoles has been developed. The reaction proceeds efficiently under mild conditions with high yields (up to 99%) and moderate to excellent enantioselectivities (up to 92%) thus providing a hitherto unavailabl...

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Bibliographic Details
Main Authors: Chew, Renta Jonathan, Huang, Yinhua, Li, Yongxin, Pullarkat, Sumod A., Leung, Pak-Hing
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/102819
http://hdl.handle.net/10220/19200
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Institution: Nanyang Technological University
Language: English