Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles
An enantioselective Michael addition reaction of diphenylphosphine to substituted alkenylisoxazoles has been developed. The reaction proceeds efficiently under mild conditions with high yields (up to 99%) and moderate to excellent enantioselectivities (up to 92%) thus providing a hitherto unavailabl...
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sg-ntu-dr.10356-1028192020-03-07T12:34:55Z Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles Chew, Renta Jonathan Huang, Yinhua Li, Yongxin Pullarkat, Sumod A. Leung, Pak-Hing School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry An enantioselective Michael addition reaction of diphenylphosphine to substituted alkenylisoxazoles has been developed. The reaction proceeds efficiently under mild conditions with high yields (up to 99%) and moderate to excellent enantioselectivities (up to 92%) thus providing a hitherto unavailable direct access to a library of chiral tertiary phosphine-functionalized isoxazoles. 2014-04-09T07:42:11Z 2019-12-06T21:00:44Z 2014-04-09T07:42:11Z 2019-12-06T21:00:44Z 2013 2013 Journal Article Chew, R. J., Huang, Y., Li, Y., Pullarkat, S. A., & Leung, P. H. (2013). Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles. Advanced Synthesis & Catalysis, 355(7), 1403-1408. 1615-4150 https://hdl.handle.net/10356/102819 http://hdl.handle.net/10220/19200 10.1002/adsc.201300164 en Advanced Synthesis & Catalysis © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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DRNTU::Science::Chemistry::Organic chemistry Chew, Renta Jonathan Huang, Yinhua Li, Yongxin Pullarkat, Sumod A. Leung, Pak-Hing Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| description |
An enantioselective Michael addition reaction of diphenylphosphine to substituted alkenylisoxazoles has been developed. The reaction proceeds efficiently under mild conditions with high yields (up to 99%) and moderate to excellent enantioselectivities (up to 92%) thus providing a hitherto unavailable direct access to a library of chiral tertiary phosphine-functionalized isoxazoles. |
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School of Physical and Mathematical Sciences |
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School of Physical and Mathematical Sciences Chew, Renta Jonathan Huang, Yinhua Li, Yongxin Pullarkat, Sumod A. Leung, Pak-Hing |
| format |
Article |
| author |
Chew, Renta Jonathan Huang, Yinhua Li, Yongxin Pullarkat, Sumod A. Leung, Pak-Hing |
| author_sort |
Chew, Renta Jonathan |
| title |
Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| title_short |
Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| title_full |
Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| title_fullStr |
Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| title_full_unstemmed |
Enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| title_sort |
enantioselective addition of diphenylphosphine to 3-methyl-4-nitro-5-alkenylisoxazoles |
| publishDate |
2014 |
| url |
https://hdl.handle.net/10356/102819 http://hdl.handle.net/10220/19200 |
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1681043627097194496 |