Microwave Method for the Synthesis of Amantadine Hydrochloride

• Main Authors: Thinh Van Nguyen, Hien Van Pham, Duong Binh Vu, Anh Tuan Dang, Vu Khac Tran, Chau Dinh Phan
• Format: บทความวารสาร
• Language: English
• Published: Science Faculty of Chiang Mai University 2019
• Online Access: http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=9530; http://cmuir.cmu.ac.th/jspui/handle/6653943832/64217
• Institution: Chiang Mai University

An easy and rapid method to prepare amantadine hydrochloride (1), which was used for the treatment of certain influenza infections type A and Parkinson’s disease was developed. In this work, we report a microwave method, which was effective in heating and saving solvents, for the synthesis of amant...