Genome screening for reducing type I polyketide synthase genes in tropical fungi associated with medicinal plants

• Main Authors: Jumpathong J., Seshime Y., Fujii I., Peberdy J., Lumyong S.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-80051547077&partnerID=40&md5=675d51d3f92639f438f5d26fc923bbfc; http://cmuir.cmu.ac.th/handle/6653943832/6464
• Institution: Chiang Mai University

The aim of this work was to employ primers, which encode ketosynthase (KS) domains designed to detect Lovastatin-type PKSs (highly reduced molecules), to identify fungal species that have the potential for polyketide production. Using this strategy we have identified twenty-three KS sequences from t...