Deoxybenzoin and flavan derivatives from the twigs of Artocarpus lakoocha
© 2019 Phytochemical Society of Europe One new deoxybenzoin, named lakoochanoside A (1), and one new flavan, named lakoochanoside B (2), along with 17 known compounds were isolated and identified from the twigs of Artocarpus lakoocha. The structures of isolated compounds were elucidated by spectros...
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| Main Authors: | , , , |
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| Format: | Journal |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063506800&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/65251 |
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| Institution: | Chiang Mai University |
| Summary: | © 2019 Phytochemical Society of Europe One new deoxybenzoin, named lakoochanoside A (1), and one new flavan, named lakoochanoside B (2), along with 17 known compounds were isolated and identified from the twigs of Artocarpus lakoocha. The structures of isolated compounds were elucidated by spectroscopic methods, especially 1D and 2D NMR spectroscopy. Cycloartocarpin (14) exhibited strong antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus with the same MIC values of 2 μg/mL. It also displayed antimalarial activity against Plasmodium falciparum K1 with an IC 50 value of 2.66 μM. |
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