Testosterone deprivation intensifies cognitive decline in obese male rats via glial hyperactivity, increased oxidative stress, and apoptosis in both hippocampus and cortex

• Main Authors: Titikorn Chunchai, Nattayaporn Apaijai, Puntarik Keawtep, Duangkamol Mantor, Apiwan Arinno, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn
• Format: Journal
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059020184&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/65383
• Institution: Chiang Mai University

© 2018 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd Aim: The study hypothesized that testosterone deprivation aggravates cognitive decline in obesity through increasing oxidative stress, glial activation, and apoptosis. Methods: Male Wistar rats (n = 24) were fed with...